Table 4.
Sensitivity of M. bovis BCG KOTap to redox compounds
| Redox compounda | Disc load (μmol) | Inhibition zoneb (mm) for M. bovis BCG strains |
|
|---|---|---|---|
| Wild type | KOTapc | ||
| Hydrogen peroxide | 80 | 15 | 18 |
| 40 | 13 | 14 | |
| Plumbagin | 0.01 | 26 | 30 |
| Diamide | 20 | 0 | 18 |
a
Dimethyl sulfoxide, which was used as the solvent for some of these compounds, had no effect on the growth of either strain (data not shown).
b
Zones of inhibition were recorded after 21 days at 37°C.
c
KOTap is M. bovis BCG with the tapTB gene inactivated.