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Simplified schematic of the S. aureus WTA biosynthetic pathway. Tunicamycin inhibits TarO and targocil inhibits the transmembrane component (TarG) of the ABC transporter (TarGH) responsible for WTA export. Nonessential early steps in the WTA pathway are indicated by green arrows; essential late steps are indicated by red arrows. Nonessential tailoring steps are omitted for clarity.
