Fig 4.

Numbers of genes in major categories affected after 30 min of targocil treatment (up/down). Fewer than 15 genes involved in central intermediary metabolism (11/2) and purine/pyrimidine biosynthesis (1/13) were affected; categories are not displayed. No significant changes were observed in the expression of genes responsible for amino acid biosynthesis, cofactor biosynthesis, DNA metabolism, fatty acid and phospholipid synthesis, protein synthesis, signal transduction, or transcription, and these categories are not displayed.