Fig 5.
Beta-lactams suppress the development of targocil resistance. (a) Clinical MRSA isolate 1784A plated on TSB agar containing DMSO shows a lawn of bacteria. (b) 1784A plated on 8× MIC targocil shows a high frequency of resistant mutants after overnight incubation. (c) 1784A plated on 0.2× MIC (5 μg/ml) oxacillin shows a lawn of bacteria after overnight incubation. (d) 1784A plated on a combination of targocil (8× MIC) and oxacillin (0.2× MIC) shows no colonies.
