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Mutated nucleotides with discriminatory power highlighted by PLS-DA
| Grouping feature | Discriminating NT mutations (PLS-DA)a |
|---|---|
| Disease | |
| CD | C369T, C426T |
| UC | T80C (V27A), T471C |
| Controls | C525T |
| Phylogenetic group | |
| A/B1 | T255G, C276G |
| B2 | G345T, A249T, A209G (N70S), G233A (S78N) |
| D | G639C, C408T |
| Adhesion class 2 | T144C, T471C |
Underlined mutations are nonsilent, mutations between parentheses are the corresponding FimH mutated amino acids, and mutations in bold are transversions.
