Table 1.

The numbers of responders for potency study days 14, 28, and 42 by dose group for AnAPN1-Alhydrogel in BALB/c mice^a

Group	Amt (μg)		No. of responders/group
	AnAPN1	Alhydrogel	Day 14	Day 28	Day 42
1		400	0	0	0
2	50.00		1	7	10
3	50.00	400.00	2	10	10
4	28.57	228.57	2	7	8
5	16.33	130.61	2	2	9
6	9.33	74.64	1	1	9
7	5.33	42.65	0	0	8
8	3.05	24.37	0	0	2
9	1.74	13.93	0	0	0
10	0.99	7.96	0	0	0
11	0.57	4.55	0	0	0
12	0.32	2.60	0	0	0
13	0.19	1.48	0	0	0
14	0.11	0.85	0	0	0
ED50 (μg)
Value			127.61	21.25	5.35
95% fiducial limits
Lower				16.37	3.00
Upper				28.28	9.05

^aMice were considered positive if the anti-AnAPN1 IgG level was above the response threshold (RT; 2 AU) established by the standard calibration curve. There were 10 mice per group.