Table 2.

Differential antibiotic susceptibility of P. aeruginosa biofilm subpopulations

Biofilm type	Antibiotic	Log reduction		P value
		GFP+ cells	GFP− cells
Arabinose-induced exptsa
Colony	Ciprofloxacin	1.21 ± 0.12	−0.48 ± 0.21	0.002
Colony	Tobramycin	3.27 ± 0.61	−1.02 ± 0.22	0.003
Arabinose removal exptsb
Colony	Ciprofloxacin	0.39 ± 0.03	2.78 ± 0.06	0.001
Colony	Tobramycin	0.08 ± 0.12	2.78 ± 0.02	0.001
Drip flow	Ciprofloxacin	1.32 ± 0.47	2.48 ± 0.58	0.184
Drip flow	Tobramycin	0.63 ± 0.38	1.72 ± 0.28	0.019

^aThe population was sorted by flow cytometry into GFP⁺ (active cell) and GFP⁻ (dormant cell) fractions.

^bThe population was sorted by flow cytometry into GFP⁺ (dormant cell) and GFP⁻ (active cell) fractions.