Table 5.
Differences in amino acid sequences of YiuR external loops
| Loop (position)a | Sequence in: |
|
|---|---|---|
| Y. kristensenii Y276c | Y. pseudotuberculosis YPIIId | |
| L1 (178–186) | QEDSNSGDI | ****K****b |
| L2 (213–229 | RSEDKIIDGYNEQRLRN | ***********Q**M** |
| L3 (253–267) | QDRNTTAGRSVALNG | **K*S*P**TL**** |
| L4 (290–314) | GNSTSYVQRDETRNPSREMKSVDNI | ******I**********Q******* |
| L5 (337–359) | EELYDEGNQLASAKDLTKLTRGS | *****K****P**S**K****W* |
| L6 (383–391) | DQDENYGTH | ***Q***** |
| L7 (417–450) | RSPDLRQATDNWGQITGGK–GDPAIIVGNSSLKPE | **********D***LS**GKG*L**L*L***N**** |
| L8 (476–518) | TDFKDKITEVRRCTDTTGKASGQCMINGNSYKFISDRTNVDKA | ***********N*DI**-NTT***VF**IN*******I***** |
| L9 (544–563) | TQSEQKSGQFSGKPLNQMPK | ********A*A*Q******* |
| L10 (587–614) | RGKTSEYLNRTSIGTTTPSYTFVDLGAN | ***A********M*SR************ |
| L11 (640–648) | NDKVLDGRR | ********* |
a
YiuR is a predicted outer membrane β-barrel with an N-terminal plug and 11 large extracellular loops. External loops were predicted by the hidden Markov model method (http://biophysics.biol.uoa.gr/PRED-MBB/).
b
Asterisks denote identical amino acid residues in both proteins.
c
Colicin FY-sensitive strain.
d
Colicin FY-resistant strain.