Table 1.
Clinical features of the four patients with blaNDM-1-carrying Klebsiella pneumoniaea
| Patient | Age (yr)/gender and underlying disease | Admission date, date discharged or expired, and clinical outcome | Ward (dates of hospital stayb) | Period of isolation of NDMKP, specimen type, and pathogenicity | Carbapenem(s) administered before isolation of NDMKP (no. of days before isolation) |
|---|---|---|---|---|---|
| 1 | 71/F; pyogenic spondylitis | 3 June 2010; 21 January 2011; improved | GW124 (3 June–5 July), MICU1 (5 July–16 July), GW134 (16 July–30 July), MICU1 (30 July–3 August), GW134 (3 August–21 January 2011) | 5 November 2010–31 December 2010; stool; colonizer | Meropenem (8) |
| 2 | 52/M; dermatomyositis interstitial lung disease | 7 October 2010; 16 December 2010; expired from pneumothorax | MICU1 (7 October–12 October), MICU2 (12 October–16 December) | 8 November 2010–12 November 2010; urine; colonizer | Meropenem (16) |
| 3 | 71/M; vertebral osteomyelitis | 31 August 2010; 15 December 2010; improved | GW134 (31 August–2 September), MICU2 (2 September–17 September), GW134 (17 September–15 December) | 16 November 2010/stool/colonizer | Meropenem (22), ertapenem (13) |
| 4 | 59/M; liver transplantation due to HBV-associated liver cirrhosis | 28 July 2010; July 2011; improved | GW91 (28 July–3 August), MICU1 (3 August–12 August), SICU (12 August–3 September), GW102 (3 September–19 September), SICU (19 September–26 September), GW102/SICU (26 September to last follow-up on 30 June 2011) | 30 November 2010–6 December 2010/urine/colonizer; 15 December 2010–22 January 2011/stool/colonizer | Meropenem (47) |
a
NDMKP, NDM-1-producing Klebsiella pneumoniae; GW, general ward; MICU, medical intensive care unit; SICU, surgical intensive care unit; M, male; F, female.
b
In 2010 unless specified.