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BEZ-235 inhibits LCMV multiplication in cultured cells. 293T cells were infected with LCMV (MOI, 0.01). After 90 min of adsorption time, the inoculum was removed, cell monolayers were washed, and fresh medium containing the indicated BEZ-235 concentration was added. At the indicated times p.i., virus titers were determined in TCS using an IFF assay (Materials and Methods).
