Postchallenge immune responses contributing to decreased viremia in macaques after s.l. immunization. (A) Env- and Gag-specific CD4+ CM responses in PBMC at 12 weeks postchallenge. (B, C) Inverse correlation of summed percentages of Env- and Gag-specific CD4+ CM cells, respectively, secreting IFN-γ, IL-2, and TNF-α with median chronic viremia.