Table 2.
Peptide no. (domain/region) |
P value for: |
|||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Very sensitive laboratory strain |
Low-sensitive primary subtype C strain |
|||||||||||||||
SF162 (R5) |
IIIB (X4) |
DU172 (R5) |
DU156 (R5) |
|||||||||||||
NTr-Mo | EUN-N | TR-Mo | HIV+N | NTr-M | EUN-N | TR-Mo | HIV+N | NTr-M | EUN-N | TR-Mo | HIV+N | NTr-M | EUN-N | TR-Mo | HIV+N | |
3 (HR1, QARILAV) | <0.001 | 0.001 | NS | NS | <0.001 | NS | NS | NS | 0.008 | NS | NS | NS | NS | NS | NS | NS |
27 (IDE) | 0.001 | 0.001 | 0.001 | NS | 0.001 | 0.001 | NS | <0.001 | ||||||||
20 (HR2, MPER, 2F5, 4E10) | 0.037 | 0.044 | 0.01 | 0.01 | 0.004 | NS | NS | NS | NS | NS | 0.05 | 0.05 | NS | NS | NS | NS |
12-B (HR2, MPER, 2F5) | 0.028 | 0.007 | 0.028 | NS | NS | NS | NS | NS | ||||||||
12-C (HR2, MPER, 2F5) | 0.001 | 0.001 | 0.001 | 0.02 | 0.001 | NS | 0.001 | 0.05 | <0.001 | <0.001 | NS | NS | NS | NS | 0.05 | 0.03 |
The analysis includes five gp41 peptides that elicited antibodies (titer, >1:20). NS, not significant. NTr-Mo, HIV-1-infected, nontransmitting mothers; EUN-N, HIV-1-exposed, uninfected newborns; TR-Mo, HIV-1-infected, transmitting mothers; HIV+N, HIV-1-infected newborns.