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. 2012 Jan 20;287(11):8444–8456. doi: 10.1074/jbc.M111.294124

FIGURE 3.

FIGURE 3.

A, the concentration of glycerol released by epididymal WAT explants taken from mice that were fed ad libitum or fasted for 6 or 24 h, showing decreased release from Angptl4−/− WAT (n = 6; *, p < 0.05 versus fed; **, p < 0.0001 versus WT 24-h fasted). Glycerol concentrations were normalized to protein. B, as in A, using inguinal WAT explants (n = 6; *, p < 0.05 versus WT fasted). C, FFA levels measured from the plasma of WT and Angptl4−/− mice that were either fed ad libitum or fasted for 24 h, showing a reduction in the fasting-induced plasma FFA levels in Angptl4−/− mice (n = 6; *, p < 0.01 versus WT fed; **, p < 0.001 versus WT fasted). D, body composition as measured by DEX, showing a lack of body fat loss induced by fasting in Angptl4−/− mice (n = 9; *, p < 0.05 versus WT fed). E, liver triglyceride content measured by TLC in response to a 24-h fast, showing a loss of fasting-induced hepatic steatosis in Angptl4−/− mice (n = 9; *, p < 0.05 versus WT fed). Error bars, S.E.