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CaMKII inhibition results in increased glutamate in conditioned neuronal media. Glutamate concentration (mean ± S.D., n = 3–6) in neuronal media following incubation with 10 μm tat-CN21 or tat-CN21Ala for varying lengths of time, as measured by a glutamate oxidase assay. *, p < 0.05 compared with vehicle control (DMSO) (one-way ANOVA, post hoc Dunnett's test).
