Figure 3.

Disease-modifying effects of MIP-1α haplotypes in the European American portion of the cohort. (a and b) The KM curves of the development of AIDS in European Americans that possess (blue) or lack (red) the ancestral MIP-1α haplotype (CC). All, the entire portion of the cohort and Sct, indicates seroconverting individuals. The reference group are individuals with the ancestral (CC) haplotype. (c and d) KM curves comparing the clinical course of European Americans with the following haplotype pairs: CC/CC (blue); CC/CT (green); and CT/CT (red). The reference group for the survival analyses is individuals that are homozygous for the ancestral MIP-1α haplotype CC (blue).