FIGURE 3.

CBM48 topology in the N′ domain. a, superposition of the eight CBM48 structures that carry the loop protruding from the seventh and eighth β-strands to the N′ domain in SMMA. b, schematic diagram showing the antiparallel β-sandwich fold for the N and N′ domains. The loop protruding from the N′ domain is colored cyan. c, the positions of the N and N′ domains at the surface of the remaining portion of the SMMA molecule. d, aromatic residues located near the loop protruding from the N′ domain. The domain has been colored in a spectrum; the N terminus is in blue, and the C terminus is in orange.