Table 1.
Comparative microarrays analysis of the gene expression between strains CSM and EC1118
| Categorya | P value | Genes upregulated in strain CSM (fold induction) |
|---|---|---|
| A | ||
| Thiamine biosynthetic process | 1.04e−6 | THI12 (10.88), THI11 (8.44), THI13 (6.71), THI5 (2.65) |
| Aryl alcohol dehydrogenase | 5.19e−13 | AAD15 (3.42), AAD10 (2.86), AAD6 (2.30), AAD14 (2.24), AAD4 (2.05), AAD3 (2.04) |
| Oxidoreductase activity | 4.82e−10 | ERG11 (2.70), ERG5 (2.66), FRE7 (2.28), MET12 (2.22), GTT1 (2.15), COX8 (2.05) |
| Others | HPA2 (4.16), RDL1 (3.92), SPG4 (3.55), RIM4 (2.97), YOR348c (2.94), RDL2 (2.82) | |
| B | ||
| Glucose metabolic process | 4.1e−12 | ENO2 (4.55), TDH3 (3.65), PFK1 (3.38), ENO1 (2.98), TDH2 (2.91), PGK1 (2.74), TPI1 (2.54) |
| Amino acid metabolic process | 8e−14 | ADH3 (4.50), ARG4 (4.09), ADH5 (4.06), MET16 (3.86), MET17 (3.71), SER33 (3.37), CYS3 (3.35), CPA1 (3.31), BAT1 (3.04), MET22 (2.92), ARO3 (2.59), MET14 (2.55) |
| Others | YIL060w (3.74), YCT1 (3.43), SPT4 (3.00), PMA1 (2.88), YCR023c (2.79), POL4 (2.63), HXT3 (2.62), JLP1 (2.60), ROG3 (2.56), PDR12 (2.54), CYR1 (2.49), HRK1 (2.37) |
a
A, functional categories overrepresented in the genes upregulated by a factor of 2 or more in strain CSM; B, functional categories overrepresented in the genes upregulated by a factor of 2 or more in strain EC1118. The induction level of each gene is shown in parentheses. In both categories, all of the genes upregulated more than 2.5-fold have been included.