Table 3.
Differentially expressed proteins by 2-DE in microalbuminuria versus normoalbuminuria.
| Gene namea | Accession numberb | Up-/down-regulated | Mol. Mass, Da (pI)c | Peptides matched | Total ion C.I.%d | Ma/Na (2-DE)f |
Ma/Na (iTRAQ)g |
|---|---|---|---|---|---|---|---|
| ALB | P02768 | Up | 71317.2 (5.92) | 2 | 100.00 | 50.8 ± 15.3 | 3.09 |
| ALB | P02768 | Up | 71317.2 (5.92) | 2 | 99.84 | 17.5 ± 4.0 | 3.09 |
| ALB | P02768 | Up | 71317.2 (5.92) | 2 | 100.00 | 14.2 ± 2.5 | 3.09 |
| HSPG | P98160 | Down | 468527.5 (6.06) | 2 | 100.00 | 0.28 ± 0.041 | 0.68 |
| FABP | Q01469 | Down | 15496.7 (6.6) | 1 | 97.76 | 0.27 ± 0.037 | 0.29 |
| MASP2 | Q9UMV3 | Down | 75684.6 (5.47) | 2 | 100.00 | 0.10 ± 0.005 | 0.29 |
| AMBP | P02760 | Down | 38974 (5.95) | 2 | 99.91 | 0.20 ± 0.002 | 1.44 |
| RTEL1 | Q9NZ71 | Up | 152278.2 (8.68) | 1 | 96.77 | 3.0 ± 0.5 | — |
| FBLN5 | Q9UBX5 | Down | 50146.7 (4.58) | 1 | 99.36 | 0.12 ± 0.007 | — |
a-bGene name from the Expasy database correspond to protein accession number. bAccession numbers represent entries in the Human CDS database. cMolecular mass (mol. mass) is presented by Da, while isoelectric point stands for pI. dTotal ion score and total ion CI % for MALDI-TOF/TOF were calculated using GPS v3.5 in the MASCOT search program (v2.0). f-gRatio of differentially excreted protein for 2-DE and iTRAQ in microalbumiuric versus normoalbuminuric urines, respectively. Data are expressed as the mean ± SD.