Table 2.
Differentially expressed genes in heat-pattern RA patient versus healthy control.
| Gene name | Definition | Accession no. | Heat/control ratio |
|---|---|---|---|
| Up-regulated gene (>1.4) | |||
| CAMP | Cathelicidin antimicrobial peptide | NM_004345 | 2.33 |
| MMGT1 | Membrane magnesium transporter 1 | AL157477 | 1.69 |
| TDRD7 | Tudor domain containing 7 | AB025254 | 1.56 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | NM_007080 | 1.54 |
| CCDC55 | Coiled-coil domain containing 55 | NM_032141 | 1.54 |
| GTF3C6 | General transcription factor IIIC, polypeptide 6, alpha 35 kDa | BC011593 | 1.54 |
| CD59 | CD59 molecule, complement regulatory protein | NM_000611 | 1.52 |
| CTLA4 | Cytotoxic T-lymphocyte-associated protein 4 | AF414120 | 1.52 |
| ASCC3 | Activating signal cointegrator 1 complex subunit 3 | AY013288 | 1.47 |
| PRKAA1 | Protein kinase, AMP-activated, alpha 1 catalytic subunit | AK024252 | 1.45 |
| BCL2A1 | BCL2-related protein A1 | NM_004049 | 1.45 |
| TMEM60 | Transmembrane protein 60 | NM_032936 | 1.43 |
| HSPA1A | Heat shock 70 kD protein 1A | NM_005345 | 1.43 |
| PARP9 | Poly (ADP-ribose) polymerase family, member 9 | NM_031458 | 1.43 |
| HIST1H1C | histone cluster 1, H1c | NM_005319 | 1.43 |
| Down-regulated gene (<1 : 1.4) | |||
| HSPA8 | Heat shock 70 kD protein 8 | NM_006597 | 0.63 |
| SLC43A3 | Solute carrier family 43, member 3 | NM_014096 | 0.67 |
| Unknown | Homo sapiens clone 24629 mRNA sequence | AF052160 | 0.67 |
| PSMD8 | Proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | NM_002812 | 0.69 |
| NCL | Nucleolin | NM_005381 | 0.70 |
| LBH | Limb bud and heart development homolog (mouse) | NM_030915 | 0.71 |