TABLE 2.
Autoimmune Disease Grouping by Immunopathology and Number of Cases Identified Through Hospital Discharge Records Between Baseline and December 31, 2005 Among 15,357 Adults by Sex: Adverse Childhood Experiences Study 1995 to 2005
| Autoimmune Disease (ICD-9 Code) | Target Organ, Tissue, or Receptor | Number of Cases |
||
|---|---|---|---|---|
| Women | Men | Total | ||
| Autoimmune diseases associated with cell-mediated, Th1-type immunopathology and/ or increased incidence in males | ||||
| Idiopathic myocarditis (422.91) | Heart | 1 | 0 | 1 |
| Idiopathic pulmonary fibrosis (515.0) | Lung | 11 | 23 | 34 |
| Insulin-dependent diabetes mellitus (250.01, 250.03, 250.13, 250.23, 250.41, 250.51, 250.61, 250.81) | Pancreas | 36 | 50 | 86 |
| Irritable bowel disease (556.0 to 556.9) | Gut | 3 | 9 | 12 |
| Wegner granulomatosis (446.4) | Arteries | 2 | 0 | 2 |
| Autoimmune diseases with mixed Th1/ Th2 responses | ||||
| Pernicious anemia (281.0) | Stomach | 4 | 13 | 17 |
| Vitiligo (709.01) | Skin | 0 | 1 | 1 |
| Addison disease (255.4) | Adrenal glands | 5 | 4 | 9 |
| Autoimmune hemolytic anemia (283.0) | Red blood cells | 3 | 6 | 9 |
| Psoriasis (696.0) | Skin | 7 | 6 | 13 |
| Celiac disease (579.0) | Gut | 3 | 6 | 9 |
| Multiple sclerosis (340.0) | Nerves | 12 | 5 | 17 |
| Autoimmune diseases associated with antibody-mediated, Th2-type immunopathology and/or increased incidence in females (includes rheumatic diseases below) | ||||
| Graves' disease (242.0) | Receptor | 13 | 4 | 17 |
| Autoimmune thrombocytopenia purpura (287.0) | Platelets | 25 | 37 | 62 |
| Myasthenia gravis (358.0) | Receptor | 5 | 5 | 10 |
| Hashimoto's thyroiditis (245.2) | Thyroid | 8 | 0 | 8 |
| Th2-type rheumatic diseases subgroup | ||||
| Scleroderma (710.1) | Collagen | 8 | 0 | 8 |
| Dermatomyositis (710.3) | Muscle | 1 | 1 | 2 |
| Systemic lupus erythematosus (710.0) | Nucleus | 26 | 4 | 30 |
| Sjogren disease (710.2) | Glands | 9 | 0 | 9 |
| Rheumatoid arthritis (714.0) | Joints | 48 | 22 | 70 |
ICD-9 = International Classification of Diseases, Ninth Revision; Th1 = T-helper 1; Th2 = T-helper 2.
Among the 372 hospital records with any diagnosis of an autoimmune disease, 15% include more than one autoimmune disease.