Appendix Table 4.

Sensitivity Analysis Results for Best Strategies Model; 50% Higher Fracture Rates^*

Screening Strategy	Lifetime Cost, $†	Quality- Adjusted Life-Years Accrued	Incremental Cost- Effectiveness Ratio†
SCORE −2.5 initiated at age 60 y with rescreening every 10 y	61 320	13.9307	NA
QUS −1.0 initiated at age 55 y with rescreening every 5 y	61 370	13.9404	5770
SCORE −2.5 initiated at age 55 y with rescreening every 5 y	61 420	13.9436	12 880
DXA −2.5 initiated at age 55 y with rescreening every 5 y	61 430	13.9445	17 560
DXA −2.0 initiated at age 55 y with rescreening every 10 y	61 810	13.9534	42 070
DXA −2.0 initiated at age 55 y with rescreening every 5 y	62 000	13.9554	99 760
DXA −1.5 initiated at age 55 y with rescreening every 10 y	62 500	13.9597	113 330
DXA −1.5 initiated at age 55 y with rescreening every 5 y	62 680	13.9611	134 030

DXA = dual-energy x-ray absorptiometry; NA = not applicable; QUS = quantitative ultrasonography; SCORE = Simple Calculated Osteoporosis Risk Estimation.

^*Strategies are described in Table 1. Costs are expressed in 2010 $US, and incremental cost-effectiveness ratios represent cost per quality-adjusted life-year gained for each strategy compared to the next less costly nondominated strategy.

^†Costs and incremental cost-effectiveness ratios are rounded off to the nearest 10.