Table 2.

Evaluation of apoptosis and caspase-8 activity in U937 cells after incubation with plasma from CRS type 1 patients and healthy volunteers

	CRS type 1 patients	Healthy controls	p value
	(n = 15)	(n = 20)
Plasma-induced apoptosis after 72 h, %	78 (52.0–93.0)	11 (10.0–12.5)	<0.001
Plasma-induced apoptosis after 96 h, %	81 (62.0–92.0)	11 (10.5–13.0)	<0.001
Caspase-8, S/B ratio	0.91 (0.75–1.02)	0.44 (0.41–0.52)	0.01

Results (median with IQR) are given as percentage of apoptotic cells/field for apoptosis at 72 and 96 h or S/B ratio for caspase-8 activity at 24 h.