FIGURE 4. Region-of-Interest-Based Comparisons Between Anxiety Disordersa.
a (Left) Hyperactivation in patients, relative to comparison subjects, was observed more frequently in the amygdala and insula of patients with either social anxiety disorder or specific phobia than in patients with PTSD. (Right) Hypoactivation in the ventromedial prefrontal cortex, rostral and dorsal anterior cingulate cortices, and thalamus was specifically observed in patients with PTSD in relation to matched comparison subjects and not in patients with social anxiety disorder or specific phobia.
*p<0.05. **p<0.01. ***p<0.005.