Table 2.
Relation of log-BNP to Body Mass Index and Waist Circumference in Hypertensive and Normotensive Jackson Heart Study Participants
Models | Model 1 | p-value | Model 2 | p-value |
---|---|---|---|---|
β coefficient (SE) | β coefficient (SE) | |||
All Participants | ||||
| ||||
Continuous | ||||
BMI | −0.084 (0.017) | <0.0001 | −0.191 (0.024) | <0.0001 |
WC | −0.057 (0.017) | 0.0006 | −0.166 (0.023) | <0.0001 |
BMI categories | ||||
Normal | Reference | Reference | ||
Overweight | −0.145 (0.053) | 0.0059 | −0.240 (0.066) | 0.0003 |
Obese | −0.271 (0.051) | <0.0001 | −0.539 (0.069) | <0.0001 |
P for Trend | <0.0001 | <0.0001 | ||
WC Categories | ||||
Low adiposity | Reference | Reference | ||
High adiposity | −0.071 (0.019) | 0.0002 | −0.172 (0.026) | <0.0001 |
P for Trend | 0.0002 | <0.0001 | ||
| ||||
Hypertensive
Participants |
||||
| ||||
Continuous | ||||
BMI | −0.055 (0.027) | 0.0228 | −0.140 (0.035) | <0.0001 |
WC | −0.042 (0.027) | 0.082 | −0.131 (0.034) | <0.0001 |
BMI categories | ||||
Normal | Reference | Reference | ||
Overweight | −0.137 (0.083) | 0.0964 | −0.250 (0.113) | 0.027 |
Obese | −0.220 (0.079) | 0.0055 | −0.457 (0.115) | <0.0001 |
P for trend | 0.006 | 0.0004 | ||
WC Categories | ||||
Low adiposity | Reference | Reference | ||
High adiposity | −0.059 (0.028) | 0.0325 | −0.151 (0.039) | 0.0001 |
P for trend | 0.033 | <0.0001 | ||
| ||||
Normotensive
Participants |
||||
| ||||
Continuous | ||||
BMI | −0.111 (0.025) | <0.0001 | −0.219 (0.033) | <0.0001 |
WC | −0.074 (0.030) | 0.0019 | −0.182 (0.033) | <0.0001 |
BMI categories | ||||
Normal | Reference | Reference | ||
Overweight | −0.137 (0.067) | 0.0416 | −0.184 (0.078) | 0.0215 |
Obese | −0.316 (0.067) | <0.0001 | −0.569 (0.087) | <0.0001 |
P for trend | <0.0001 | <0.0001 | ||
WC Categories | ||||
Low adiposity | Reference | Reference | ||
High adiposity | −0.082 (0.026) | 0.0014 | −0.168 (0.034) | <0.0001 |
P for trend | 0.0014 | <0.0001 |
p<0.0001;
p<0.001;
p<0.05
Model 1 = adjustment for BMI plus age, history of myocardial infarction, diabetes mellitus, current smoking, blood pressure stage (systolic blood pressure <140 and diastolic blood pressure <90 mm Hg; systolic blood pressure 140 to 159 or diastolic blood pressure 90 to 99 mm Hg; systolic blood pressure ≥160 or diastolic blood pressure ≥100 mm Hg, or use of antihypertensive therapy), and serum creatinine,
Model 2 = Model 1 + adjustment for echo left atrial size, echo left ventricular mass, and echo left ventricular systolic dysfunction.