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. Author manuscript; available in PMC: 2012 Apr 4.
Published in final edited form as: Int J Comput Biol Drug Des. 2011 Feb 4;3(4):334–349. doi: 10.1504/IJCBDD.2010.038396

Figure 2. Illustration of two amino acid substitutions (A111V and T119N) in human HBA2.

Figure 2

a) Structural representation of the A111V mutation. The wild-type chain A is shown in green color, mutant chain A in cyan, wild-type chain B in yellow, and mutant chain B in orange. The amino acid residue Ala 110 (wild-type) is shown in magenta, and Val 110 (mutant) in white.

b) Structural representation of T119N. Chains A and B are shown in green and yellow, respectively. The residue Asn 119 (wild-type) is shown in pink, and Thr 119 (mutant) in blue.

c) Multiple sequence alignment of HBA2 with the amino acid substitution sites indicated.