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The effects of five amino acid substitutions on protein-protein interaction. The unit of energy change is kcal/mol.
| Amino acid substitution | A111V (HBA2) | T119N (HBA2) | Q61K (HRAS) | A146T (HRAS) | A693V (ZBTB20) |
|---|---|---|---|---|---|
| ΔΔΔGbinding | −11.56 | 0.90 | −7.29 | −0.21 | −0.31 |
| ΔΔΔGFoldX | −1.41 | 1.39 | −2.40 | −0.11 | 0.00 |
