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. Author manuscript; available in PMC: 2012 Apr 4.
Published in final edited form as: Cancer Res. 2009 Nov 10;69(23):8910–8917. doi: 10.1158/0008-5472.CAN-09-1543

Figure 3.

Figure 3

Tangeretin-cisplatin combination induces G2/M arrest in A2780/CP70 cells. Cells were treated with either 150 μM tangeretin or its vehicle for 24 hours, followed by treatment with cisplatin or its vehicle for another 72 hours. The cell cycle distribution and apoptosis of drug treated cells were analyzed using flow cytometry (A&B). Symbol** represent significant difference at p<0.001 the corresponding single treatment groups by Tukey-Kramer Multiple Comparisons Test; n=3. C, Cyclin B1, Cdc25C and p53 were determined by Western blot analysis.