Table 4.
Multivariate analysis of characteristics associated with the presence of negative-strand hepatitis C virus (HCV) RNA in peripheral blood mononuclear cells in 315 samples, controlling for repeated measures in 144 anti-HCV–positive/HIV-infected women.
| Characteristic | OR (95% CI) | P |
|---|---|---|
| Alcohol use, drinks/week | ||
| 0 | 1.0 | |
| 1–6 | 1.2 (0.6–2.5) | .54 |
| ≥7 | 2.9 (1.2–7.1) | .02 |
|
| ||
| IDU in past 6 months | ||
| No | 1.0 | |
| Yes | 0.2 (0.1–0.9) | .03 |
|
| ||
| Plasma HCV RNA level, log copies/mL | ||
| >0 to <6.0 | 1.0 | |
| 6.0 to <6.75 | 1.4 (0.5–4.1) | .52 |
| ≥6.75 | 4.6 (1.1–19.9) | .04 |
| HCV RNA negative | 0.4 (0.1–1.7) | .22 |
|
| ||
| CD4+CD38+DR+ cells, % | ||
| <10 | 1.0 | |
| ≥10 | 0.5 (0.3–1.0) | .05 |
|
| ||
| AIDS diagnosis | ||
| No | 1.0 | |
| Yes | 2.0 (1.0–3.9) | .05 |
NOTE. Analyses used logistic regression with generalized estimating equations for repeated measures within subjects. CI, confidence interval; IDU, injection drug use; OR, odds ratio.