Fig 2.

Illustration of time point definitions. Time point t_n (strained state) was defined as maximum LV pressure for beat 1 (t_n1) and beat 2 (t_n2). Time point t₀ (reference state) was defined as last time frame before mitral leaflet separation (as represented by the rapid increase in plotted curve of distances (cm) between marker #33 and #4, see Fig 1) for beat 1 (t₀₁) and beat 2 (t₀₂).