Skip to main content
. Author manuscript; available in PMC: 2012 Aug 15.
Published in final edited form as: Biochem J. 2011 Aug 15;438(1):33–37. doi: 10.1042/BJ20110009

Figure 2. PTC induction of ABCB1 is mediated by CCK2R in Caco-2 cells.

Figure 2

(A) Three cell lines were treated with different concentrations of PTC for 45 min at 37 °C. The media was collected and analyzed for CCK by EIA assay. (B) mRNA level for receptors of CCKs and GLPs in Caco-2 cells was analyzed by RT-qPCR. (C) Caco-2 cells were pretreated with CCK2R antagonist, YM022 (10 μM) for 2 h, and then PTC was added to the cultured cells for 9 h. mRNA level for ABCB1 was analyzed by RT-qPCR. Data are mean ± SEM, n=3 for three separate experiments.