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Physical characteristics of polylactide-co-gycolide (PLGA) and PEGylated PLGA nanoparticles
| Formulation | Particle size and range (90th percentile, nm) |
Zeta Potential (mV)a |
|---|---|---|
| A (PLGA:50/50) | 210 (85–353) | −26.24 ± 5.2 |
| B (tri-block, 10% PEG) | 335 (91–648) | −7.45 ± 0.90 |
| C (di-block, 5% PEG) | 166 (72–351) | −4.50 ± 0.69 |
| D (di-block, 10% PEG) | 171 (70–433) | −9.36 ± 1.09 |
| E (di-block, 15% PEG) | 114 (73–324) | −2.8 ± 1.60 |
Each reading represents the mean of triplicate samples ± SD.
