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Effect of prodrugs on the survival of cultured cancer cell lines. A. MDA-MB-468 cells were treated with a single dose of the indicated compounds for 72 h. B. MDA-MB-468 cells were treated daily with 34 and 35 for three days. Cell viability in panels A and B was determined by MTT assays. C. Cancer cell lines were treated daily with 34 for three days. D. Cancer cell lines were treated daily with 40 for three days. Cell viability in panels C and D was determined by SRB assays.
