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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: J Neuroendocrinol. 2012 May;24(5):789–797. doi: 10.1111/j.1365-2826.2011.02272.x

Figure 7.

Figure 7

The effect of 17β-estradiol (E2) on α,β-meATP-induced [Ca2+]i transients in Wt, ERαKO, and ERβKO mice. (a) Wt mouse as a control, (b) ERαKO mouse, E2 added for 5min didn’t inhibit α,β-meATP-induced [Ca2+]i transient in control vs. after E2 treatment. (c) In ERβKO mouse, E2 stimulation significantly attenuated the α,β-meATP-stimulated [Ca2+]i transient similar to that observed in Wt mouse. Summary data represented on the right bar graphs. Values are expressed as mean±SEM. Δ[Ca2+]i were determined by subtracting the [Ca2+]i peak levels from the basal [Ca2+]i levels. *Statistically significant difference from control, p < 0.05.