Table 1.
Translational Diffusion Coefficients (Dt) for DMPC In q = 0.3 Bicelle Mixtures
| Bicelle (Detergent/Lipid) | Weight % (Detergent + Lipid) | Detergent CMC1 (mM) | Temp K | Dt for Bicelles (×10−11m2/s) (Bicelle Preparative Method B) | Effective Hydrodynamic Radius of Bicelles (Å) (Bicelle Preparative Method B) | Dt for Bicelles (×10−11m2/s) (Bicelle Preparative Method A) | Effective Hydrodynamic Radius of Bicelles (Å) (Bicelle Preparative Method A) |
|---|---|---|---|---|---|---|---|
| DPC/DMPC | 12% | 2 | 303 | 8.9±0.2 | 25±1 | 7.2±0.1 | 31±1 |
| D6PC/DMPC | 12% | 14 | 303 | 10.4±0.3 | 22±1 | 9.5±0.1 | 24±1 |
| D6PC/DMPC | 6% | 14 | 303 | 13.9±0.3 | 16±1 | 13.1±0.1 | 17±1 |
| D6PC/DMPC | 3% | 14 | 303 | ND2 | ND | 14.4±0.1 | 16±1 |
| D6PC/DMPC | 1.5% | 14 | 303 | ND | ND | 13.9±0.1 | 16±1 |
| D6PC/DMPC | 1% | 14 | 303 | 18.5±0.3 | 12±1 | 13.4±0.1 | 17±1 |
| D6PC/DMPC | 0.5% | 14 | 303 | ND | ND | No bicelles | No bicelles |
| D6PC/DMPC | 0.25% | 14 | 303 | ND | ND | No bicelles | No bicelles |
| D6PC/DMPC | 0.1% | 14 | 303 | ND | ND | No bicelles | No bicelles |
| D7PC/DMPC | 12% | 1.5 | 303 | 4.0±0.2 | 56±3 | 4.4±0.1 | 51±1. |
| D7PC/DMPC | 6% | 1.5 | 303 | 6.4±0.2 | 35±1 | 6.8±0.1 | 32±1 |
| D7PC/DMPC | 3% | 1.5 | 303 | ND | ND | 8.4±0.1 | 27±1 |
| D7PC/DMPC | 1.5% | 1.5 | 303 | 18.0±0.2 | 12±1 | 9.1±0.1 | 25±1 |
| D7PC/DMPC | 0.5% | 1.5 | 303 | ND | ND | 9.8±0.2 | 23±1 |
| D7PC/DMPC | 0.25% | 1.5 | 303 | 20±0.2 | 11±1 | 9.7±0.3 | 23±1 |
| D7PC/DMPC | 0.1% | 1.5 | 303 | 18.4±0.4 | 12±1 | 10.0±0.3 | 22±1 |
| D8PC/DMPC | 12% | 0.3 | 303 | ND | ND | 0.20±0.01 | 1134±57 |
| D8PC/DMPC | 6% | 0.3 | 303 | ND | ND | 0.19±0.01 | 1194±63 |
| D8PC/DMPC | 3% | 0.3 | 303 | ND | ND | 0.27±0.01 | 840±31 |
| D8PC/DMPC | 1.5% | 0.3 | 303 | ND | ND | 1.1±0.1 | 207±19 |
| D8PC/DMPC | 1% | 0.3 | 303 | ND | ND | 1.1±0.1 | 207±19 |
| D8PC/DMPC | 0.5% | 0.3 | 303 | ND | ND | 2.2±0.1 | 103±5 |
| D8PC/DMPC | 0.25% | 0.3 | 303 | ND | ND | 3.2±0.1 | 71±3 |
| D8PC/DMPC | 0.1% | 0.3 | 303 | ND | ND | 4.7±0.2 | 48±2 |
| Cyclofos-4/DMPC | 12% | 8.5 | 303 | 8.3±0.3 | 27±1 | 6.9±0.1 | 33±1 |
| Cyclofos-5/DMPC | 12% | 4.5 | 303 | 10±0.2 | 22±1 | 7.1±0.1 | 32±1 |
| Cyclofos-7/DMPC | 12% | 0.6 | 303 | 9.5±0.1 | 23±1 | 7.0±0.1 | 32±1 |
| Cyclofos-6/DMPC | 12% | 2.7 | 303 | 10.5±0.2 | 21±1 | 8.4±0.1 | 27±1 |
| Cyclofos-6/DMPC | 12% | 2.7 | 313 | 21.3±0.3 | 12±1 | 16.0±0.1 | 16±1 |
| Cyclofos-6/DMPC | 12% | 2.7 | 293 | 6.6±0.2 | 26±1 | 5.2±0.1 | 33±1 |
| Cyclofos-6/DMPC | 6% | 2.7 | 303 | 14.7±0.3 | 15±1 | 9.4±0.1 | 24±1 |
| Cyclofos-6/DMPC | 3% | 2.7 | 303 | 14.2±0.3 | 16±1 | 11.0±0.1 | 20±1 |
| Cyclofos-6/DMPC | 1.5% | 2.7 | 303 | 16.4±0.2 | 14±1 | 11.0±0.1 | 20±1 |
| Cyclofos-6/DMPC | 0.75% | 2.7 | 303 | ND | ND | 10.5±0.1 | 21±1 |
| Cyclofos-6/DMPC | 0.5% | 2.7 | 303 | 15.0±0.5 | 15±1 | 10.6±0.4 | 21±2 |
| Cyclofos-6/DMPC | 0.3% | 2.7 | 303 | 13.1±0.3 | 17±1 | 6.8±0.1 | 33±1 |
| Cyclofos-6/DMPC | 0.2% | 2.7 | 303 | ND | ND | No bicelles | No bicelles |
| Cyclofos-6/DMPC | 0.1% | 2.7 | 303 | ND | ND | No bicelles | No bicelles |