Transmission-blocking effect of anti-mosquito midgut mAb MG25E, MG24C,
or MG4B, on P. vivax development in An.
gambiae (filled bars) and An. stephensi (open
bars) mosquitoes. (a) Oocyst infection prevalence in
mosquitoes allowed to feed on MG25E (n = 18 and 22
for An. gambiae and An. stephensi,
respectively), MG24C (n = 3 and 15), MG4B
(n = 9 and 11), Ab control (n =
28 and 37), or chimpanzee serum control (n = 28 and
39) is expressed as geometric means. * denotes statistical
significance at the 0.05 level as compared with the chimpanzee and Ab
control groups. (b) Oocyst infection intensity is
expressed as geometric mean ± SEM of infected mosquitoes fed
MG25E, MG24C, MG4B, Ab control, or chimpanzee control. * denotes
statistical significance at the 0.05 level as compared with the
chimpanzee and Ab control groups.