Table 1.
Baseline characteristics of participants with and without peripheral arterial disease according to baseline body mass index (n=686)
| Participants with Peripheral Arterial Disease | Participants without Peripheral Arterial Disease | |||||||
|---|---|---|---|---|---|---|---|---|
| BMI 20-25 kg/M2 (n=108) | BMI 25-30 Kg/M2 (n=184) | BMI >30 Kg/M2 (n=134) | P trend | BMI 20-25 kg/M2 (n=61) | BMI 25-30 Kg/M2 (n=98) | BMI >30 Kg/M2 (n=105) | P trend | |
| Age, years (SD) | 76.4 (8.9) | 75.2 (8.6) | 73.3 (6.7) | 0.003 | 72.9 (8.2) | 71.5 (6.8) | 70.6 (7.6) | 0.056 |
| Black race, % | 17.6 | 11.4 | 22.6 | 0.232 | 8.2 | 23.2 | 23.8 | 0.027 |
| Male sex, % | 43.5 | 63.0 | 54.5 | 0.133 | 34.4 | 50.0 | 43.8 | 0.355 |
| Ankle Brachial Index (SD) | 0.61 (0.15) | 0.64 (0.15) | 0.63 (0.16) | 0.202 | 1.12 (0.09) | 1.10 (0.09) | 1.06 (0.10) | <0.001 |
| Diabetes mellitus, % | 23.2 | 30.4 | 46.3 | <0.001 | 13.1 | 15.8 | 36.2 | <0.001 |
| Angina, % | 30.2 | 39.0 | 36.1 | 0.368 | 15.00 | 17.89 | 24.27 | 0.134 |
| Myocardial Infarction (%) | 25.0 | 22.9 | 32.3 | 0.169 | 14.8 | 11.2 | 18.1 | 0.446 |
| Stroke (%) | 25.9 | 19.6 | 22.6 | 0.583 | 9.84 | 9.47 | 6.67 | 0.440 |
| Heart Failure (%) | 25.9 | 28.3 | 34.3 | 0.135 | 11.5 | 13.7 | 16.2 | 0.393 |
| Knee osteoarthritis (%) | 13.0 | 9.2 | 17.3 | 0.260 | 14.8 | 13.7 | 26.7 | 0.035 |
| Hip osteoarthritis (%) | 4.6 | 0.00 | 7.5 | 0.156 | 0.00 | 4.2 | 5.7 | 0.089 |
| Calf muscle area, mm2 (SD) | 4,928 (901) | 5,649 (1,388) | 5,742 (1,687) | <.0001 | 5,350 (1,168) | 5,806 (1,530) | 6,603 (1,567) | <.0001 |
| Calf muscle density, gm/cm3 (SD) | 33.4 (3.6) | 33.2 (3.8) | 30.9 (4.5) | <.0001 | 34.9 (3.8) | 34.1 (3.6) | 32.5 (4.1) | <.0001 |
| Calf muscle percent fat, % (SD) | 7.1 (7.0) | 9.9 (10.6) | 17.3 (17.5) | <.0001 | 6.9 (9.9) | 9.5 (12.0) | 12.2 (12.8) | 0.005 |
| Isometric knee extension strength, newtons (SD) | 237 (85) | 286 (112) | 297 (118) | <0.001 | 268 (97) | 298 (133) | 298 (109) | 0.177 |
| Knee extension power, watts (SD) | 81 (41) | 95 (50) | 103 (60) | 0.002 | 104 (44) | 128 (70) | 115 (58) | 0.481 |
SD = Standard Deviation