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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: J Steroid Biochem Mol Biol. 2012 Jan 12;130(1-2):7–15. doi: 10.1016/j.jsbmb.2011.12.012

Fig. 4.

Fig. 4

Formation of androgens from Δ4-Adione in (A) LNCaP and (B) LNCaP-AKR1C3 cells in the presence or absence of finasteride and indomethacin. Cells were treated with 0.1 μM Δ4-Adione alone or in combination with 2.0 μM finasteride or 30 μM indomethacin. Error bars represent standard deviation of the mean n=3. Gluc: glucuronidase treatment; * p<0.05 vs LNCaP cells without inhibitor; ** p<0.05 vs LNCaP-AKR1C3 cells without inhibitor. 4-Androstenedione: Δ4-Adione; 5α-Adione: 5α-androstane-3,17-dione; -Gluc: glucuronidated form.