Table 2.
Locus | Ancestral allele | No. of variant alleles
|
||
---|---|---|---|---|
Mutation | Import | Translocation | ||
iga | iga2 | 1 (iga1) | 1 (iga3) | |
IS1106A | Uncertain | 8 (IS1106A4-11)* | ||
pgm | pgm3 | 1 (pgm11) | 1 (pgm19) | |
opaB | opaB92 | 1 (opaB93)† | 2 (opaB94,5202) | 12 (5× opaA; 4× opaD; 3× opaJ)† |
opaD | opaD131 | 1 (opaD100) | 8 (7× opaJ; 1× opaB)† | |
tbpB | tbpB1 | 28 (19× family 1; 6× family 4; 3× family 3) |
The mechanism by which one additional IS1106A allele (IS1106A99) arose is unclear because that allele is associated with a 12-kb region that has not been sequenced (see supplemental data).
The mutation in opaB93 is a 12-bp deletion. Translocations into opaB: from opaA: opaB102, 113, 115, 139, 141; from opaD: opaB100, 114, 131, 1131; from opaJ: opaB116, 140, 142. Translocations into opaD: from opaJ: opaD101, 108, 109, 110, 111, 112, 1101; from opaB: opaD94.