Table 2.
subject | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| |||||||||||||
mean | SD | ||||||||||||
|
|||||||||||||
1 week before the dose | 2581 | 2769 | 1427 | 4047 | 2856 | 1256 | 1650 | 1661 | 1532 | 8034 | 2781 | 2041 | |
| |||||||||||||
dose 1 | baseline | 2795 | 2364 | 1503 | 684 | 4892 | 2757 | 1476 | 1052 | 4195 | 3382 | 2510 | 1374 |
2 hours | 6149 | 1793 | 3501 | 1266 | 13420 | 2433 | 6850 | 10100 | 6378 | 8570 | 6046 | 3922 | |
4 hours | 7768 | 10900 | 8122 | 1458 | 5673 | 6467 | 2420 | 15919 | 6136 | 10630 | 7549 | 4233 | |
6 hours | 1737 | 1690 | 1824 | 2844 | 2541 | 2199 | 1911 | 1610 | 5355 | 5807 | 2752 | 1545 | |
24 hours | 4168 | 1672 | 2018 | 1236 | 2541 | 1362 | 1606 | 871 | 2789 | 4436 | 2270 | 1218 | |
48 hours | 5137 | 1087 | 4776 | 971 | 2362 | 1423 | 2006 | 5556 | 1744 | 8203 | 3326 | 2438 | |
120 hours | 4464 | 2664 | 2154 | 780 | 3389 | 2157 | 3792 | 815 | 1271 | 3394 | 2488 | 1277 | |
| |||||||||||||
dose 2 | baseline | -a | 1666 | 1803 | 1855 | - | 2328 | 1657 | 2684 | 1108 | 1043 | 1768 | 554 |
2 hours | - | 3787 | 2623 | 4591 | - | 32230 | 16090 | 35330 | 8094 | 8841 | 13950 | 12960 | |
4 hours | - | 9532 | 1533 | 7570 | - | 8323 | 2840 | 86630 | 22040 | 1479 | 17490 | 28720 | |
6 hours | - | 3693 | 935 | 4195 | - | 2782 | 1960 | 3551 | 2969 | 10500 | 3823 | 2889 | |
24 hours | - | 1631 | 1710 | 1973 | - | 1867 | 1780 | 2271 | 15650 | 2896 | 3722 | 4837 | |
48 hours | - | 1598 | 419 | 2535 | - | 3264 | 2072 | 1461 | 2176 | 1582 | 1888 | 841 | |
120 hours | - | 1717 | 3738 | 628 | - | 1022 | 1902 | 1987 | 2959 | 762 | 1839 | 1082 | |
| |||||||||||||
dose 3 | baseline | 1466 | 1108 | 2019 | 1417 | 1338 | 242 | 2341 | 443 | 1546 | 1039 | 1296 | 638 |
2 hours | 13610 | 4935 | 32440 | 5071 | 31890 | 9003 | 10610 | 43430 | 33090 | - | 20450 | 14640 | |
4 hours | 12260 | 17300 | 18360 | 4875 | 14230 | 7273 | 6338 | 11990 | 28860 | 39890 | 16140 | 10900 | |
6 hours | - | 452 | 15100 | 3668 | 831 | 859 | 1047 | 3723 | 20470 | 4397 | 5616 | 7181 | |
24 hours | 551 | 461 | 11270 | 1634 | 240 | 316 | 754 | 872 | 2028 | 1469 | 1960 | 3326 | |
48 hours | 1815 | 1420 | 3084 | 2201 | 853 | 1679 | 538 | 1118 | 1021 | - | 1525 | 779 | |
120 hours | 10020 | 369 | 861 | 1706 | 494 | 361 | 1093 | 186 | 1124 | 1156 | 1737 | 2948 | |
168 hours | 791 | 318 | 608 | 4087 | 361 | 264 | 600 | 326 | 426 | - | 865 | 1221 |
Values missing due to poor recovery of N2-ethyl-dGuo.