Table 2.
THCCOOH (ng/l) concentrations in expectorated oral fluid from 10 participants before and after smoking a single 6.8% THC cigarette.
| Time (h) | −0.5 | 0.25 | 0.5 | 1 | 2 | 3 | 4 | 6 | 22 |
|---|---|---|---|---|---|---|---|---|---|
| A | 17.5 | <LOQ* | NC | 51.0 | 49.3 | 20.1 | 34.0 | 24.0 | 6.0 |
| B | 39.2 | NC | NC | NC | 64.8 | 12.3 | 18.5 | <LOQ | <LOQ |
| C | 8.4 | <LOQ* | <LOQ* | <LOQ* | 37.1 | <LOQ | 14.3 | 23.9 | 7.7 |
| D | 28.0 | 97.1 | 82.6 | 66.4 | 78.2 | 37.5 | 74.6 | 30.1 | 22.6 |
| E | 57.0 | 148 | 157 | 274 | 94.1 | 54.2 | 67.9 | 66.8 | DC |
| F | 56.9 | <LOQ* | <LOQ* | 220 | 314 | 127 | 125 | 151 | DC |
| G | 98.3 | 468 | NC | 561 | 244 | 62.7 | 96.6 | 23.7 | 24.0 |
| H | 26.8 | 271 | NC | 57.2 | 62.6 | 50.5 | 25.0 | 33.5 | 14.2 |
| I | 11.5 | 20.8 | 24.5 | 22.8 | 19.9 | 9.1 | 15.6 | 17.0 | DC |
| J | 581 | 537 | 488 | 462 | 3519 | 372 | 424 | 529 | DC |
| Median a | 28 | 148 | 82.6 | 66.4 | 64.8 | 44.0 | 34.0 | 27.0 | 14.2 |
NC- not collected due to dry mouth; DC -discharged at 6 h from the unit;
<LOQ – below limit of quantification: THCCOOH –5 ng/l;
<LOQ* – below limit of quantification in low volume specimens for THCCOOH (250 ng/l), due to a required 50-fold dilution.
a
Median – participant J excluded due to blood in oral fluid