Table 5.
Recommended SAMHSA, DRUID and proposed cannabinoid concentration cutoffs for expectorated oral fluid specimens following controlled smoked cannabis.
| Cutoffs | # Positive a / Total b |
% Positive |
Time of last positive (range) h |
Median Time of last positive, h |
Positive baseline specimens |
|---|---|---|---|---|---|
| THC ≥THC ≥ 1 μg/l (DRUID) | 59/63 | 93.7% | 4 - >22 | 6 | 2 |
| THC ≥ 2 μg/l (SAMHSA) | 55/63 | 87.3% | 2 - >22 | 6 | 1 |
| CBD ≥ 1 μg/l | 35/62 | 56.5% | 1 - 6 | 2 | 0 |
| THC ≥ 1 μg/l & CBD ≥ 1 μg/l | 35/62 | 56.5% | 1 - 6 | 2 | 0 |
| THC ≥ 2 μg/l & CBD ≥ 1 μg/l | 35/62 | 56.5% | 1 - 6 | 2 | 0 |
| CBN ≥ 1 μg/l | 38/61 | 62.3% | 1 - 6 | 4 | 0 |
| THC ≥ 1 μg/l & CBN ≥ 1 μg/l | 38/61 | 62.3% | 1 - 6 | 4 | 0 |
| THC ≥ 2 μg/l & CBN ≥ 1 μg/l | 38/61 | 62.3% | 1 - 6 | 4 | 0 |
| THCCOOH ≥ 15 ng/l | 48/57 | 84.2% | 4 - >22 | 6 | 7 |
| THC ≥ 1 μg/l & THCCOOH ≥ 15 ng/l | 43/57 | 75.4% | 4 - 6 | 6 | 2 |
| THC ≥ 2 μg/l & THCCOOH ≥ 15 ng/l | 42/57 | 73.7% | 2 - 6 | 6 | 1 |
| THCCOOH ≥ 20 ng/l | 44/57 | 77.2% | 1 - >22 | 6 | 6 |
| THC ≥ 1 μg/l & THCCOOH ≥ 20 ng/l | 40/57 | 70.2% | 1 - 6 | 6 | 2 |
| THC ≥ 2 μg/l & THCCOOH ≥ 20 ng/l | 40/57 | 70.2% | 1 - 6 | 6 | 1 |
| THCCOOH ≥ 25 ng/l | 35/57 | 61.4% | ND - 6 | 5 | 6 |
| THC ≥ 1 μg/l & THCCOOH ≥ 25 ng/l | 34/57 | 59.6% | ND - 6 | 4 | 2 |
| THC ≥ 2 μg/l & THCCOOH ≥ 25 ng/l | 34/57 | 59.6% | ND - 6 | 4 | 1 |
ND – not detected; DRUID – Driving under the Influence of Drugs, Alcohol and Medicines; SAMHSA – Substance Abuse and Mental Health Services Administration
a
Number of positive specimens after cannabis smoking
b
Total number of specimens evaluated in the category
Data exclude specimens from participant J due to blood in oral fluid