Figure 6.
Altered spine density in the PFC and BLA pyramidal neurons after stress in BDNF+/Met and WT mice. A, Spine density in apical dendrites of PFC pyramidal neurons in BDNF+/Met and WT mice. B, Representative photomicrographs of apical dendritic spines from PFC pyramidal neurons. Scale bar, 10 μm. C, Spine density in basal dendrites of PFC pyramidal neurons in BDNF+/Met and WT mice. D, Spine density in apical dendrites of BLA pyramidal neurons in BDNF+/Met and WT mice. E, Representative photomicrographs of apical dendritic spines from BLA pyramidal neurons. Scale bar, 10 μm. F, Spine density in basal dendrites of BLA pyramidal neurons in BDNF+/Met and WT mice. All values (n = 7 per group) are presented as mean ± SEM (*p < 0.05, **p < 0.01, compared with home cage same-genotype mice; #p < 0.05, ##p < 0.01, compared with stress WT mice).