(A) Oil-red O staining of cytosolic lipids in the CrebH null and wild-type control primary hepatocytes after the treatment of vehicle, TM (5μg/ml), or PA (100μM) for 12 hours (magnification: 400x). (B) Fat tolerance test for the CrebH null and wild-type control mice. Mice were fasted for 16 hours, followed by oral gavage of pure olive oil at the dose of 12 μl/g body weight. Plasma TG levels were determined immediately before and at 2, 4, 6, and 8 hours after olive oil loading. The mean ± SEM (n=5) values were shown.