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. Author manuscript; available in PMC: 2012 Apr 4.
Published in final edited form as: Curr Top Med Chem. 2011;11(16):2103–2115. doi: 10.2174/156802611796575948

Fig. (3).

Fig. (3)

Comparison of the HGXPRT reaction (A) to similar reactions in which the transition state structures have been solved by the combination of kinetic isotope effects and computational chemistry described in the text. The reaction in (B) is for purine nucleoside phosphorylase and in (C) for orotate phosphoribosyltransferase. The pyrophosphate products are not showed.