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. Author manuscript; available in PMC: 2012 Apr 4.
Published in final edited form as: Gastroenterology. 2008 Jun 4;135(3):926–936.e2. doi: 10.1053/j.gastro.2008.05.079

Figure 7.

Figure 7

The histogram shows the calculated geometric centers from bone marrow transplanted chimera mice. The first bar demonstrates that the bone marrow transplant procedure itself does not alter gastrointestinal transit, as the fluorescent marker progressed to the distal regions of the small bowel over a period of 90 minutes, similar to naïve controls. The second grey bar shows that surgical manipulation of WT mice transplanted with Egr-1+/+ bone marrow exhibit significant ileus. However, in contrast, manipulated WT mice transplanted with Egr-1−/− bone marrow display significant protection from the development of postsurgical ileus (hatched bar). The fourth solid colored bar representing the averaged geometric center of manipulated KO mice transplanted with Egr-1+/+ bone marrow illustrates that Egr-1 present only in bone marrow derived cells also develop a significant degree of postoperative ileus. (N=4,4,4 and 3, ANOVA with Bonferroni posthoc analysis, *=p<0.05).