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. Author manuscript; available in PMC: 2012 Apr 5.
Published in final edited form as: Circ Res. 2011 Feb 24;108(8):985–995. doi: 10.1161/CIRCRESAHA.110.233775

Figure 1. Identification of distinct macrophage sub-populations in human atherosclerotic plaques.

Figure 1

Panel A. Immunostaining (top row) and higher magnification (bottom rows) of representative stainings for CD68, MR and Oil red O in human carotid atherosclerotic lesions. Scale bars are shown.

Panel B. Q-PCR analysis of IL-4 performed on RNA from LCM isolated CD68+MR− and CD68+MR+ macrophage-rich areas. mRNA levels were normalized to cyclophilin mRNA and expressed relative to the levels in CD68+MR− area set at 1. Each point corresponds to a single atherosclerotic plaque. The median value is shown. Statistically significant differences are indicated (t-test; *p< 0.05).