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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Cytokine. 2012 Feb 21;58(2):245–252. doi: 10.1016/j.cyto.2012.01.012

Figure 5. Sustained treatment of BMSC or HOB with melphalan decreases IL-6 mRNA expression.

Figure 5

BMSC (A) or HOB (B) were left untreated or treated with melphalan [50μg/ml] for 4 or 16 hours. Following treatment, RNA was isolated and quantitated and real-time PCR completed to evaluate changes in IL-6 mRNA expression in chemotherapy treated cells as compared to their untreated controls treated controls. Melphalan treatment decreases IL-6 mRNA in both BMSC and HOB after 16 hours of exposure.