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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Cytokine. 2012 Feb 21;58(2):245–252. doi: 10.1016/j.cyto.2012.01.012

Figure 7. Melphalan decreases IL-6 protein in a co-culture with myeloma cells.

Figure 7

BMSC and H929 (A) and HOB and H929 (B) cells were co-cultured for 24 hours. After 24 hours, co-cultures were left untreated or exposed to melphalan [50ug/ml] for 24 hours. Following treatment, cells were rinsed, media replaced, supernatants collected at 2, 4, 6 and 8 hours post-treatment and an IL-6 ELISA completed. Melphalan exposure significantly decreased IL-6 protein expression. Log transformed ANOVA and Tukey post hoc tests were used for statistical analysis (* represents p<0.05).