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. 2012 Apr;11(3):291–302. doi: 10.1111/j.1601-183X.2012.00766.x

Figure 2. Impact of RF on food intake, EE, RER and activity in Mc3r−/−and WT mice.

Figure 2

Data shown are recordings taken at 18-min intervals and averaged by genotype; breaks in the data stream indicate times when the system was dismantled for cleaning. Dark and light periods are indicated by the black and white rectangles situated above the top panel; timing of food access is indicated by gray shading. (a) Cumulative food intake. (b) EE data expressed as kJ/h/mouse. EE declined with RF, food access was associated with increased EE due to the thermic effect of food. (c) RER data. RER declined to 0.7 in the intervals between food access irrespective of genotype, indicating mobilization of fat reserves. An increase in the RER during feeding is consistent with oxidation of the low fat diet. (d) Physical activity was assessed using X-movements.