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. 2012 Apr 4;7(4):e35024. doi: 10.1371/journal.pone.0035024

Figure 1. Isoproterenol (ISO) pairing with olfactory nerve theta burst stimulation (TBS) induced mitral cell (MC) spike potentiation.

Figure 1

A1 . Single MC spiking patterns before and 30 min following TBS induction in the presence of the β-adrenoceptor agonist isoproterenol (10 µM). Arrow indicates the time of the single olfactory nerve test stimulus. A2&A3 . Peristimulus spike frequency histograms (binning 50 ms) under the control condition (red) and 20–30 min after TBS induction of the example cell in A1 (A2); and of the average of n = 10 cells in the same condition (A3). B . Peristimulus spike frequency histograms under the control condition and 20–30 min after TBS induction in the absence of ISO (n = 10). C . Peristimulus spike frequency histogram under the control condition and 20–30 min following a brief (5 min) application of ISO. D . Histogram comparing mean spike frequencies during the 250 ms intervals before (spontaneous) and after the olfactory nerve stimulation (evoked) under control conditions (red) and 20–30 min post-inductions (black). **p<0.01 *p<0.05. Error bars, mean±SEM.